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INTRAOSSEOUS INJECTIONS

INTRA-OSSEOUS OR (IO) INJECTIONS INVOLVE INJECTING PLATELETS RICH IN GROWTH FCTOR OR BONE MARROW CONCENTRATE INTO A BONE TO TREAT SEVERE FORMS OF OSTEOARTHRITIS. 

The most advanced, minimally invasive treatment at OrthoRegen® is Intra-osseous injections.  This treatment is reserved for patients with severe osteoarthritis and MRI findings of subchondral oedema.  It is also a treatment used for patients with Osteochondral Defects or OCD lesions.  Subchondral oedema is a significant pain generator in severe osteoarthritis.  It is indicative of small cracks or micro-fractures within the bone and is a sign that the bone beneath the cartilage is weak.  Subchondral oedema shown on MRi correlates with pain more tham cartilage loss on X-Ray or the presence of a joint effusion.  This finding is also a sign that the osteoarthritis is actively progressing.

The OrthoRegen® team are among the first in Australia to use IO injections for the management of severe osteoarthritis.  We have had the pleasure of meeting the undisputed father of intra-osseous injections, Dr Phillipe Hernigou (France) at international conferences and been honoured to receive advanced training in this technique by world leaders in the USA.  

   DOES THE PROCEDURE HURT?

 

Intra-ossoues injections are performed under local anaesthetic and Nitric Oxide in the OrthoRegen® treatment rooms.  Most patients are surprised at how little the procedure hurts.  On occasion, it can be performed under twilight sedation in an outpatient surgical centre.

   HOW IS THE RECOVERY?

 

For most patients, 48-72 hours of increased discomfort can be expected.  It is common to actually experience some relief in pain from your condition as the treatment can reduce the pressure inside the bone providing temporary relief.  Healing of the subchondral oedema will take weeks to months following the treatment.

   WHAT PATIENTS ARE CANDIDATES FOR IO INJECTIONS?

 

Patients suffering from severe osteoarthritis with or without subchondral oedema lesions on their MRI are candidates for this procedure.  Patients have usually failed conservative measures and are interested in avoiding surgery or are not surgical candidates.

   RESEARCH

Current Concepts in Intraosseous Platelet-Rich Plasma Injections for Knee Osteoarthritis

Diego Delgadoa, Ane Garatea, Hunter Vincent, Ane Miren Bilbao, Rikin Patel, Nicolás Fiz, SteveSampson, Mikel Sánchez

Combination of Intra-articular and Intraosseous Injections of Platelet Rich Plasma for Severe Knee Osteoarthritis - A Pilot Study

Mikel Sanchez et al

 

Intraosseous Infiltration of Platelet Rich Plasma for Severe Hip Osteoarthritis

Nicolas Fiz et al

Subchondral Stem Cell Therapy versus Contralateral Total Knee Arthroplasty for Osteoarthritis following Osteonecrosis of the Knee

Phillipe Hernigou et al