In recent years, there has been a growing interest in the use of biologic therapies for osteoarthritis and musculoskeletal injuries, such as platelet-rich plasma (PRP), microfragmented adipose tissue (MFAT) and bone marrow aspirate concentrate (BMAC). These therapies are based on the injection of autologous (from the same person) cells or substances that have regenerative and anti-inflammatory properties. Among these, MFAT has shown promising results in preclinical and clinical studies for the treatment of OA and other musculoskeletal problems.

 

Microfragmented Adipose Tissue (MFAT) Therapys

At our regenerative medicine clinic, we utilize Microfragmented Adipose Tissue (MFAT) therapy—an innovative, natural treatment designed to help repair and regenerate damaged joints, tendons, and soft tissues. This minimally invasive approach uses your body’s own fat tissue to support healing, reduce inflammation, and improve function in musculoskeletal conditions.

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What is Microfragmented Adipose Tissue?

Microfragmented adipose tissue is created from a small amount of your own fat, typically taken from the abdominal area or thighs using a gentle liposuction technique. This fat is then mechanically processed—without the use of enzymes or additives—to preserve the naturally occurring mesenchymal stem cells (MSCs), pericytes, and other regenerative elements found in the adipose tissue.

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The result is a highly concentrated, purified solution of MFAT that can be precisely injected into damaged joints or soft tissue areas to support healing and restoration.

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What Are Mesenchymal Stem Cells (MSCs)?

MSCs are multipotent stem cells found in various tissues, including bone marrow and adipose (fat) tissue. They are capable of differentiating into cartilage, bone, tendon, muscle, and other tissue types, making them invaluable in orthopaedic and regenerative treatments.

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In addition to their regenerative potential, MSCs are known for their powerful anti-inflammatory and immunomodulatory effects. When injected into an area of injury or degeneration, MSCs help:

• Reduce inflammation

• Modulate immune response

• Recruit and stimulate native cells to repair damaged tissue

• Promote the growth of new blood vessels (angiogenesis)

• Protect and support existing cartilage

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Research has shown that adipose-derived MSCs remain more abundant and viable than those derived from bone marrow, especially in older patients. This makes adipose tissue an ideal source for regenerative orthopaedic therapies.

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How the MFAT Procedure Works?

The procedure is performed in our clinic under local anesthesia and typically takes about 60–90 minutes.

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Step-by-Step Overview:

1. Harvesting
   A small amount of fat (usually 40–100 ml) is collected via a gentle mini-liposuction, most often from the abdomen or flanks.

2. Processing
   The fat is mechanically microfragmented using a closed, sterile system such as Lipo-Stem or similar technology. This isolates and concentrates regenerative elements while preserving the natural structure and viability of the MSCs and surrounding matrix.

3. Injection
   The MFAT is then carefully injected under ultrasound guidance into the targeted area—such as a knee, hip, shoulder, or tendon—to ensure precise delivery to the site of injury or degeneration.

4. Recovery
   Because this is a minimally invasive outpatient procedure using your own tissue, downtime is typically minimal. Most patients return to normal activities within a few days.

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Conditions Commonly Treated with MFAT

• Osteoarthritis (knee, hip, shoulder, ankle)

• Tendinopathies (rotator cuff, Achilles tendon, tennis elbow)

• Labral and meniscal injuries

• Cartilage degeneration

• Joint instability

• Post-surgical repair enhancement

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Expected Results and Outcomes

Patients often begin to notice improvement within 4 to 12 weeks, with continued healing and functional gains for up to 6–12 months.

Benefits reported include:

• Reduced joint pain and stiffness

• Improved mobility and range of motion

• Decreased inflammation

• Enhanced tissue repair and regeneration

• Reduction in the need for long-term medications or surgery

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Results vary depending on the individual’s condition, age, and overall health. However, clinical studies have demonstrated significant improvements in pain, joint function, and quality of life for many orthopaedic patients using MFAT therapy.

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Why Choose Microfragmented Adipose Therapy?

• Autologous (from your own body) and natural

• No enzymes, additives, or cell expansion

• Minimal downtime and low risk of complications

• Proven safety profile with strong regenerative potential

• Backed by emerging clinical evidence and research

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Ready to Restore and Regenerate?

If you're living with joint pain, stiffness, or soft tissue injuries, microfragmented adipose tissue therapy may offer a safe and effective alternative to surgery or long-term medications. Contact our clinic today to schedule a consultation and learn more about this cutting-edge regenerative option.

 

How to get started with MFAT therapy?

If you are interested in our MFAT and want to find out if you are a good candidate, you can visit our CONTACT PAGE.  OrthoRegen® will provide you with a comprehensive assessment and a personalised treatment plan that will help you achieve your health and wellness goals. 

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For further information on other services and treatments we provide, please head to OUR SERVICES page.